There is a launch of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to decrease afferent soreness transmission and create analgesia. Therefore, medications like clonidine that focus on alpha-2 receptors can impact the transmission of ache. Applies to clonidine: oral tablet, https://7prbookmarks.com/story19810517/the-greatest-guide-to-onolidine